PCWorld explains how Safe Mode serves as a critical troubleshooting tool when Windows fails to boot by loading only essential system components. Safe Mode enables users to identify problematic drivers, uninstall recent programs, run system repairs like SFC and DISM, and access System Restore. Key diagnostic tools include boot logging to identify crash-causing drivers, Device Manager for driver rollbacks, and startup management through Task Manager. If your Windows PC won't start properly or keeps crashing, Safe Mode can help you identify the cause and fix the problem. In Safe Mode, Windows only loads the most essential drivers and services, skips third-party autostart programs, and uses a simple graphical user interface. This allows you to disable faulty drivers, software, or malware-since these do not run in Safe Mode.

Tokyo Electric Power Company Holdings (Tepco) said Saturday that an alert system did not work during a test operation held the day prior as part of the restart of the No. 6 reactor at its Kashiwazaki-Kariwa nuclear plant in Niigata Prefecture. The company is working to identify the cause of the problem, but failure to resolve it soon may affect its plan to restart the reactor on Tuesday. According to Tepco, the problem was confirmed at 12:36 p.m., and it stopped the test operation. The alert system is designed to activate when a control rod is being pulled out of the reactor while another rod is already out. The Kashiwazaki-Kariwa reactor would be the first of Tepco's nuclear reactors to be restarted since the March 2011 accident at its tsunami-crippled Fukushima No. 1 nuclear plant.

Multi-layered distributed representation is believed to be the key ingredient of deep neural networks especially in cognitive tasks like computer vision. While non-differentiable models such as gradient boosting decision trees (GBDTs) are still the dominant methods for modeling discrete or tabular data, they are hard to incorporate with such representation learning ability. In this work, we propose the multi-layered GBDT forest (mGBDTs), with an explicit emphasis on exploring the ability to learn hierarchical distributed representations by stacking several layers of regression GBDTs as its building block. The model can be jointly trained by a variant of target propagation across layers, without the need to derive backpropagation nor differentiability. Experiments confirmed the effectiveness of the model in terms of performance and representation learning ability.

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the machine learning literature focus solely on improving the prediction accuracy of a patient's pathology. We argue that this objective is insufficient to ensure doctors' acceptability of such systems. In their initial interaction with patients, doctors do not only focus on identifying the pathology a patient is suffering from; they instead generate a differential diagnosis (in the form of a short list of plausible diseases) because the medical evidence collected from patients is often insufficient to establish a final diagnosis. Moreover, doctors explicitly explore severe pathologies before potentially ruling them out from the differential, especially in acute care settings. Finally, for doctors to trust a system's recommendations, they need to understand how the gathered evidences led to the predicted diseases.

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text pretraining paradigms to incorporate medical knowledge, these approaches primarily rely on implicitly encoded knowledge within model parameters, neglecting task-specific knowledge required by diverse downstream tasks. To address this limitation, we propose Retrieval-Augmented Diagnosis (RAD), a novel framework that explicitly injects external knowledge into multimodal models directly on downstream tasks. Specifically, RAD operates through three key mechanisms: retrieval and refinement of disease-centered knowledge from multiple medical sources, a guideline-enhanced contrastive loss that constrains the latent distance between multi-modal features and guideline knowledge, and the dual transformer decoder that employs guidelines as queries to steer cross-modal fusion, aligning the models with clinical diagnostic workflows from guideline acquisition to feature extraction and decision-making. Moreover, recognizing the lack of quantitative evaluation of interpretability for multimodal diagnostic models, we introduce a set of criteria to assess the interpretability from both image and text perspectives. Extensive evaluations across four datasets with different anatomies demonstrate RAD's generalizability, achieving state-of-the-art performance. Furthermore, RAD enables the model to concentrate more precisely on abnormal regions and critical indicators, ensuring evidence-based, trustworthy diagnosis. Our code is available at https://github.com/tdlhl/RAD.

This paper studies the key problems of bearing fault diagnosis of high-speed train. As the core component of the train operation system, the health of bearings is directly related to the safety of train operation. The traditional diagnostic methods are facing the challenge of insufficient diagnostic accuracy under complex conditions. To solve these problems, we propose a novel Neural Factorization-based Classification (NFC) framework for bearing fault diagnosis. It is built on two core idea: 1) Embedding vibration time series into multiple mode-wise latent feature vectors to capture diverse fault-related patterns; 2) Leveraging neural factorization principles to fuse these vectors into a unified vibration representation. This design enables effective mining of complex latent fault characteristics from raw time-series data. We further instantiate the framework with two models CP-NFC and Tucker-NFC based on CP and Tucker fusion schemes, respectively. Experimental results show that both models achieve superior diagnostic performance compared with traditional machine learning methods. The comparative analysis provides valuable empirical evidence and practical guidance for selecting effective diagnostic strategies in high-speed train bearing monitoring.

Loss of lung function in cystic fibrosis (CF) occurs progressively, punctuated by acute pulmonary exacerbations (PEx) in which abrupt declines in lung function are not fully recovered. A key component of CF management over the past half century has been the treatment of PEx to slow lung function decline. This has been credited with improvements in survival for people with CF (PwCF), but there is no consensus on the optimal approach to PEx management. BEAT-CF (Bayesian evidence-adaptive treatment of CF) was established to build an evidence-informed knowledge base for CF management. The BEAT-CF causal model is a directed acyclic graph (DAG) and Bayesian network (BN) for PEx that aims to inform the design and analysis of clinical trials comparing the effectiveness of alternative approaches to PEx management. The causal model describes relationships between background risk factors, treatments, and pathogen colonisation of the airways that affect the outcome of an individual PEx episode. The key factors, outcomes, and causal relationships were elicited from CF clinical experts and together represent current expert understanding of the pathophysiology of a PEx episode, guiding the design of data collection and studies and enabling causal inference. Here, we present the DAG that documents this understanding, along with the processes used in its development, providing transparency around our trial design and study processes, as well as a reusable framework for others.

The abundance of fine-grained spatio-temporal data, such as traffic sensor networks, offers vast opportunities for scientific discovery. However, inferring causal relationships from such observational data remains challenging, particularly due to unobserved confounders that are specific to units (e.g., geographical locations) yet influence outcomes over time. Most existing methods for spatio-temporal causal inference assume that all confounders are observed, an assumption that is often violated in practice. In this paper, we introduce Spatio-Temporal Hierarchical Causal Models (ST-HCMs), a novel graphical framework that extends hierarchical causal modeling to the spatio-temporal domain. At the core of our approach is the Spatio-Temporal Collapse Theorem, which shows that a complex ST-HCM converges to a simpler flat causal model as the amount of subunit data increases. This theoretical result enables a general procedure for causal identification, allowing ST-HCMs to recover causal effects even in the presence of unobserved, time-invariant unit-level confounders, a scenario where standard non-hierarchical models fail. We validate the effectiveness of our framework on both synthetic and real-world datasets, demonstrating its potential for robust causal inference in complex dynamic systems.

AI/ML models have rapidly gained prominence as innovations for solving previously unsolved problems and their unintended consequences from amplifying human biases. Advocates for responsible AI/ML have sought ways to draw on the richer causal models of system dynamics to better inform the development of responsible AI/ML. However, a major barrier to advancing this work is the difficulty of bringing together methods rooted in different underlying assumptions (i.e., Dana Meadow's "the unavoidable a priori"). This paper brings system dynamics and structural equation modeling together into a common mathematical framework that can be used to generate systems from distributions, develop methods, and compare results to inform the underlying epistemology of system dynamics for data science and AI/ML applications.

Perhaps the most prominent current definition of (actual) causality is due to Halpern and Pearl. It is defined using causal models (also known as structural equations models). We abstract the definition, extracting its key features, so that it can be applied to any other model where counterfactuals are defined. By abstracting the definition, we gain a number of benefits. Not only can we apply the definition in a wider range of models, including ones that allow, for example, backtracking, but we can apply the definition to determine if A is a cause of B even if A and B are formulas involving disjunctions, negations, beliefs, and nested counterfactuals (none of which can be handled by the Halpern-Pearl definition). Moreover, we can extend the ideas to getting an abstract definition of explanation that can be applied beyond causal models. Finally, we gain a deeper understanding of features of the definition even in causal models.